Interpretative Bias: Indicators of Cognitive Vulnerability to Depression

Objectives: The study aimed at testing the existence of interpretative bias in remitted depressives as compared to unipolar depressives and never-depressed individuals. Method: Cognitive Bias Questionnaire was administered on 10 individuals each with unipolar depression, remitted depression, and never-depressed participants. Participants were presented with vague and ambiguous vignettes of potentially problematic situation that individuals often encounter their daily lives. Each vignette is followed by four questions with four response options reflecting a depressed-distorted, depressed-nondistorted, nondepressed-distorted, or nondepressed-nondistorted option. Participants choose the response option that best represents how they would respond to the situation if it actually happened to them. Results: Unipolar depressives interpret their condition as high on depressive mood symptoms as well as distorted thoughts whereas remitted depressives interpret their condition as high on distorted thoughts alone. Conclusions: It may suggest that despite of reduction in level of symptomatic severity of depression, cognitive errors are still maintained during remission, can increase one’s vulnerability for relapse. It implies that management of depression should focus on reducing cognitive vulnerability to depression, rather than only targeting a reduction in the symptoms (German J Psychiatry 2008; 11: 98-102).